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SYMPOSIA: Standardization of the terminology for expression of analytical results for isoflavones.

Monday, August 21, 2006 from 8 am to 3 pm

Chaired by Dr. Stephen Barnes of the University of Alabama at Birmingham, hosted by The University Of Mississippi and sponsored by the Office of Dietary Supplements of NIH. Located in the Oxford Conference Center. The intent of the workshop is to stimulate discussion. The outcome is expected to be a white paper on standardization of nomenclature of the expression of results of isoflavone analysis.

Agenda:

8:00 - 8:05

Introductory remarks

8:05 - 8:35

Opening statement of the problem
  • NIH/ODS perspective, Dr. Joseph M. Betz
  • Industry perspective – Warren Lancaster
  • Biologist's and investigators perspective, Dr. Thomas Clarkson
8:35 - 8:55
Chemistry of the isoflavones (in soy, kudzu and other dietary supplements) – Dr. Stephen Barnes
8:55 - 9:15
Isoflavones: What do users want to know? – Dr. Leila Saldanha
9:15 - 9:35
Recovery of isoflavones from supplement matrices – Dr. Jeevan Prasain
9:35 - 9:55
Available reference standards – Jana Hildreth
9:55 - 10:30
Break
10:30 - 10:50
LC-UV-diode array and LC-ion trap MS – Dr. Adrian A. Franke
10:50 - 11:20
Methylated and prenylated isoflavones – Dr. Richard van Breeman
11:20 - 11:40
LC-MS analysis of C-glycosides – Dr. Jeevan Prasain
11:40 - 12:00
change to Summary of other isoflavone assays (CE, immunoassay, NIR) – Dr Stephen Barnes
12:00 - 1:00
Lunch (Provided)
1:00 - 2:30
Discussion - topics
  • What is needed from NIH?
  • Who makes the standards?
  • How to standardize extraction?
  • Are LC-MS methods essential? Alternatives?
  • Is hydrolysis necessary?
  • Do malonates and acetates matter?
  • Units of concentration?
2:30 - 3:00
Summary of the points made and recommendations

To register click here

Invited Speakers:

Dr. Kristiina Wähälä, University of Helsinki
Dr. Adrian A. Franke, Cancer Research Center of Hawaii
Dr. Richard B. van Breemen, University of Illinois at Chicago
Dr. Thomas Clarkson, Wake Forest University Health Sciences
Dr. Jeevan Prasain, University of Alabama at Birmingham
Dr. Joseph M. Betz, Office of Dietary Supplements of NIH
Mr. Warren Lancaster, Novogen, Limited
Dr. Stephen Barnes, UAB Department of Pharmacology and Toxicology.
Dr. Leila Saldanha, NutrIQ LLC
Ms. Jana Hildreth, AOAC - International

The conference is going to be held at the Oxford Conference Center www.oxfordconferencecenter.com


For additional information, please contact:

Ikhlas Khan, Ph.D.
Assistant Director
National Center for Natural Products Research
School of Pharmacy
Thad Cochran Research Center
The University of Mississippi
University, MS 38677
Phone: (662) 915-7821
Fax: (662) 915-7989
E-mail: ikhan@olemiss.edu

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